KMID : 0358320090500030241
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Korean Journal of Urology 2009 Volume.50 No. 3 p.241 ~ p.245
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A Study of Minimal Change in Nocturia Affecting Quality of Life
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Shim Jong-Baeg
Lee Seong-Ho Kim Ha-Young
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Abstract
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Purpose: It is well known that nocturia is a bothersome symptom that affects the quality of life (QoL). However, it is not known how much of a decrease in nocturnal frequency is needed to improve the QoL. We determined the minimal change in nocturnal frequency affecting the QoL of patients with nocturia.
Materials and Methods: A total of 87 patients with BPH and nocturia were treated with ¥á-blocker and desmopressin for 8 weeks. Considering that the minimal clinically important change (MCIC) is different according to
the baseline value, we divided the patients into two groups (group I, II). Group I had mild to moderate nocturia with voiding £¼4 times per night, and Group II had severe nocturia with voiding ¡Ã4 times per night. Voiding diaries and King¡¯s Health Questionnaires (KHQs) were evaluated before and after treatment. To determine the minimal change in nocturia affecting the QoL, statistical analysis was performed by Student¡¯s t-test and ANOVA test with the change in KHQ score according to decreased numbers of nocturnal frequency.
Results: Groups I and II had 35 and 52 patients, respectively. The minimal decrease in nocturnal frequency associated with a statistically significant decrease in sleep/energy domain scores was 1 time in Group I and 2 times
in Group II.
Conclusions: These data show that decreases in nocturia of at least 1 time in patients with mild to moderate nocturia (£¼4 times/night) and of 2 times in patients with severe nocturia (¡Ã4 times/night) are needed to
improve the QoL.
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KEYWORD
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Nocturia, Quality of life
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